Dosing and Administration of Lioresal® Intrathecal (baclofen injection)
- Lioresal® Intrathecal provides targeted delivery for individual relief of severe spasticity
- Dosing options are flexible and should be tailored to meet individual patient needs in order to maintain tone as near normal as appropriate
- For long-term management of severe spasticity, the SynchroMed® II programmable pump system (Medtronic) is surgically implanted under the skin of the abdomen to deliver calculated doses of Lioresal® Intrathecal to meet individual patient needs, whether they be a “steady state” of baclofen delivered consistently throughout the day or doses timed to address spasticity when it most often occurs1
- Medtronic’s SynchroMed® II infusion pump can be programmed to fine-tune dosing—something that is not feasible with oral baclofen1
- Lioresal® Intrathecal is intended for use by the intrathecal route in single bolus test doses (via spinal catheter or lumbar puncture) and, for chronic use, only in implantable pumps approved by the FDA specifically for the administration of Lioresal® Intrathecal into the intrathecal space. Lioresal® Intrathecal is not recommended for intravenous, intramuscular, subcutaneous or epidural administration.
- Lioresal® Intrathecal (baclofen injection) for intrathecal injection [prescribing information]. Saol Therapeutics, Roswell, Georgia; January 2019.