take a look at the 100% sterile refill kit¹

Redesigned* for 100% sterility and efficiency

When we asked healthcare professionals like you what could be done to improve pump refills, they told us: minimize contamination risk with a 100% sterile presentation and streamline packaging to mirror the clinical flow. So we did, because with your work, there’s no room for error.


Learn more about identifying severe spasticity in your patients with:


Lioresal® Intrathecal is indicated for use in the management of severe spasticity. Patients should first respond to a screening dose of intrathecal baclofen prior to consideration for long term infusion via an implantable pump. For spasticity of spinal cord origin, intrathecal baclofen therapy via an implantable infusion system should be reserved for patients unresponsive to oral baclofen or those who experience intolerable central nervous system (CNS) side effects at effective doses. Patients with spasticity due to traumatic brain injury should wait at least one year after the injury before consideration of long term intrathecal baclofen therapy.


*Sterile kit.
Based on feedback from healthcare professionals who manage IT baclofen pumps.

  1. Saol Therapeutics Inc. Data on file: NDA 020075 Lioresal; 3.2.P.8 Stability and 3.2.P.8.2 Post-Approval Stability Protocol and Stability Commitment.

Important Safety Information for Lioresal® Intrathecal (baclofen injection)

Abrupt discontinuation of intrathecal baclofen, regardless of the cause, has resulted in sequelae that include high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity, that in rare cases has advanced to rhabdomyolysis, multiple organ-system failure and death.

Prevention of abrupt discontinuation of intrathecal baclofen requires careful attention to programming and monitoring of the infusion system, refill scheduling and procedures, and pump alarms. Patients and caregivers should be advised of the importance of keeping scheduled refill visits and should be educated on the early symptoms of baclofen withdrawal. Special attention should be given to patients at apparent risk (e.g. spinal cord injuries at T-6 or above, communication difficulties, history of withdrawal symptoms from oral or intrathecal baclofen). Consult the technical manual of the implantable infusion system for additional postimplant clinician and patient information (see WARNINGS).

Indications and Usage


Select Warnings and Precautions

Adverse Reactions

Common Adverse Reactions

Serious Adverse Reactions

Postmarketing Experience

Use in Specific Populations

For more information, including BOXED WARNING, refer to Lioresal® Intrathecal (baclofen injection) prescribing information.